While metformin carries the risk of lactic acidosis, one study reported that 66 of 70 metformin patients who sub- sequently developed lactic acidosis had at least one contraindication prior to use 154 .
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2 mg dl , treatment with amaryl-mp metformin hydrochloride tablets up to 2000 mg day for up to 16 weeks mean duration of treatment 11 weeks resulted in a significant mean net reduction in fpg of 64.